The role of nuclear medicine and other imaging modalities in Article - 1

The role of nuclear music and other imaginativeness modalities in hyperthyrodism - Article ExampleIn clinical practice different hyper thyroidal conditions much(prenominal) as Graves disease, hyperthyroid goiter, and other conditions such as toxic multinodular or nodular goitre wishing assessment of activity of the gland. In this review, contemporary literature has been reviewed to update current knowledge on this topic. This assigning reveals that radionuclide imaging is an important diagnostic modality in the workup of hyperthyroid disorders, but despite that, in some cases the diagnostic yield is better with ultrasonography or PET scanning. In some cases, combined use of these imaging investigations pinpoints the diagnosis in a more suitable manner. Review of these articles and the knowledge apparent may be used to frame a guideline of advice regarding imaging practice in this area.The thyroid gland produces both hormones, namely, thyroxin (T4) and triiodothyronine (T3). The se are known to play important physiological roles in the human body. Anatomically, the thyroid gland is located in the neck, in front of the trachea. It comprises of two lobes, right and left, connected by a narrow bridge of thyroid tissue, known as isthmus. It is a very highly vascular organ. The mean(prenominal) adult thyroid gland consists of follicles lined by thyroid follicular cells that contain large total of thyroglobulin. This serves as the protein precursor of the thyroid hormones (Broome, 2006). Endocrinologically, increased need for thyroid hormone leads to a signal driveway mediated by thyroid stimulating hormone ( thyroid-stimulating hormone) leading to release of active hormone from a bound state with thyroglobulin to a free state, eventually being secreted into the blood stream. When there is hypersecretion of thyroid hormones payable to any cause, the condition is known as hyperthyroidism. Usually hyperthyroidism is indicated by an elevated level of TSH. Theref ore, in clinical practice the diagnosis of hyperthyroidism is made by finding an abnormally elevated TSH level which